2-(1H-benzo[d]imidazol-2-yl)-4-bromophenol
2-(1H-benzimidazol-2-yl)-4-bromo-phenol
CAS: 62871-28-7
Molecular Formula: C13H9BrN2O
2-(1H-benzo[d]imidazol-2-yl)-4-bromophenol - Names and Identifiers
2-(1H-benzo[d]imidazol-2-yl)-4-bromophenol - Physico-chemical Properties
| Molecular Formula | C13H9BrN2O |
| Molar Mass | 289.13 |
| Density | 1.652 |
| Melting Point | 256-257℃ |
| Boling Point | 486.6°C at 760 mmHg |
| Flash Point | 248.1°C |
| Vapor Presure | 4.31E-10mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.742 |
2-(1H-benzo[d]imidazol-2-yl)-4-bromophenol - Introduction
2-(1H-benzimidazol-2-yl)-4-bromo-phenol is an organic compound with the chemical formula C13H9BrN2O. It has a benzene ring and a benzimidazole ring in which the bromine atom is stitu on one of the hydrogen atoms on the benzene ring. It is a solid with colorless or yellowish crystals with the characteristic odor of phenol.
2-(1H-benzimidazol-2-yl)-4-bromo-phenol has a variety of applications. Due to its phenolic properties, it can be used as an antibacterial agent and antiseptic. In addition, it is also used in the synthesis of other organic compounds, such as pharmaceutical intermediates and dyes.
The method for preparing 2-(1H-benzimidazol-2-yl)-4-bromo-phenol usually involves a substitution reaction of the benzene ring. A common preparation method is the reaction of 2-aminoacetophenone with NH4Br and bromine in aqueous solution to yield 2-(1H-phenyl [d] imidazole-2-)-4-bromoacetophenone. Next, the carbonyl group is reduced to a phenol group by a hydrogenation reaction catalyzed by an acid to obtain the final product 2-(1H-benzimidazol-2-yl)-4-bromo-phenol.
Regarding the safety information of 2-(1H-benzimidazol-2-yl)-4-bromo-phenol, it is necessary to pay attention to its irritating effect on skin, eyes and mucous membranes. Wear protective gloves and goggles during handling. In addition, when used or stored, the compound should be placed in a dry, well-ventilated place to avoid contact with oxidizing agents.
2-(1H-benzimidazol-2-yl)-4-bromo-phenol has a variety of applications. Due to its phenolic properties, it can be used as an antibacterial agent and antiseptic. In addition, it is also used in the synthesis of other organic compounds, such as pharmaceutical intermediates and dyes.
The method for preparing 2-(1H-benzimidazol-2-yl)-4-bromo-phenol usually involves a substitution reaction of the benzene ring. A common preparation method is the reaction of 2-aminoacetophenone with NH4Br and bromine in aqueous solution to yield 2-(1H-phenyl [d] imidazole-2-)-4-bromoacetophenone. Next, the carbonyl group is reduced to a phenol group by a hydrogenation reaction catalyzed by an acid to obtain the final product 2-(1H-benzimidazol-2-yl)-4-bromo-phenol.
Regarding the safety information of 2-(1H-benzimidazol-2-yl)-4-bromo-phenol, it is necessary to pay attention to its irritating effect on skin, eyes and mucous membranes. Wear protective gloves and goggles during handling. In addition, when used or stored, the compound should be placed in a dry, well-ventilated place to avoid contact with oxidizing agents.
Last Update：2024-04-09 21:04:16
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